Modelling the epidemiological impact of intermittent preventive treatment against malaria in infants.
BACKGROUND: Trials of intermittent preventive treatment against malaria in infants (IPTi) using sulphadoxine-pyrimethamine (SP) have shown a positive, albeit variable, jerome brown jersey protective efficacy against clinical malaria episodes.The impact of IPTi in different epidemiological settings and over time is unknown and predictions are hamper